Current Practical Cure Projects
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Stem Cell Educator
Tianhe Stem Cell Biotech, Hackensack NJ and Bejing China (5 trials)
Research Pathways:
Immune System Modification
Cell RegenerationPhase I
Estimated completion December 2022Phase II/III
Paused due to COVID-19Description: Stem Cell Educator therapy is an immune system retraining method. The therapy attempts to stop the T1D autoimmune attack by modifying a person's white blood cells, so they no longer attack insulin-producing beta cells.
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OMEGA-3 & Vitamin D in High Dose
DRI/University of Miami, Miami, FL
Research Pathways:
Immune System Modification
Cell RegenerationPhase I
Estimated completion December 2023Phase II/III
Paused due to COVID-19Description: Combination of Omega-3 and Vitamin D is designed to halt immune system response and preserve resdiual B-cell function. Two oral drugs.
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Pancreatic Endoderm Cells
Research Pathways:
Cell Transplant
EncapsulationPhase I
Estimated completion January 2021Phase II/III
Paused due to COVID-19Description: Precursor cells, derived by an embryonic stem cell line, mature into unctional beta cells when implanted under the skin. Cells are protected by add encapsulation device.
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PipepToIDC
Research Pathways:
Immune System Modification
Cell RegenerationPhase I
Estimated completion December 2022Phase II/III
Paused due to COVID-19Description: Immunotherapy vaccine composed of the patient's cultured immune cells, a beta cell protein, and vitamin D3 touches the immune system to stop attacking beta cells and reducing inflammation.
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Umbillical Cord Blood Regulatory T Cells Plus Liraglutide
Research Pathways:
Immune System Modification
Cell RegenerationPhase I
Estimated completion December 2022Phase II/III
Paused due to COVID-19Description: Stem Cell Educator therapy is in immune system retaining method. The therapy attempts to stop the T1D autoimmune attack by modifying a person’s white blood cells, so they no longer attack insulin-producing beta cells.
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Repeat BCG Vaccinations for the Treatment of Pediatric Type 1 Diabetes
Research Pathways:
Cell Regeneration
Immune System ModificationPhase II/III
Estimated completion March 2027Description: The BCG vaccine is an avirulent tuberculosis strain historically given to protect against tuberculosis. Researchers believe administering a particular strain of BCG to people with T1D will balance the overactive autoimmune attack while regenerating the insulin-producing cells that remain present even in people who have had T1D for many years.
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MSC-tolDC
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Research Pathways:
Immune System Modification
Cell RegenerationPhase I
Estimated completion December 2023Phase I/II
Description: T1D patients are administered with their own white blood cells combined with Vitamin-D3 and cultivated with stem cells. The hope is that modifying the immune system in this way will induce beta cell regeneration.
Historical Practical Cure Projects since 2012
